The Creation of Adam is a fresco painting by Michelangelo, forming part of the Sistine Chapel ceiling, painted circa 1511–1512. It illustrates the Biblical creation narrative from the Book of Genesis in which God breathes life into Adam, the first man. The fresco is part of a complex iconographic scheme and is chronologically the fourth in the series of panels depicting episodes from Genesis. It is the most well-known of the Sistine Chapel fresco panels, and its fame as a piece of art is rivaled only by the
Mona Lisa by Leonardo da Vinci.
The image of the near-touching hands of God and Adam has become iconic of humanity and has been reproduced in countless imitations and parodies. Leonardo da Vinci's Last Supper and Michelangelo's Creation of Adam are the most replicated religious paintings of all time.